Resources
Publications & research
Peer-reviewed papers and resources spanning crossbreeding, genomics, polyploidy, POMS resistance, and sustainable aquaculture.
Crossbreeding for Higher Yield and Resilience
Hybrid Vigor in Pacific Oysters: An Experimental Approach Using Crosses Among Inbred Lines.
Crossbreeding for Higher Yield and Resilience · Nov 2019
Hedgecock, D., D. J. McGoldrick, and B. L. Bayne. 1995. Hybrid vigor in Pacific oysters: An experimental approach using crosses among inbred lines. Aquacultu…
Bivalve Genomics: Complications, Challenges, and Future Perspectives.
Crossbreeding for Higher Yield and Resilience · Nov 2019
Curole, J. P., and D. Hedgecock. 2007. Chapter 29. Bivalve genomics: Complications, challenges, and future perspectives. In: Aquaculture Genome Technologies,…
Bayesian Hierarchical Modeling of Yield in Incomplete Diallel Crosses of the Pacific Oyster Crassostrea Gigas.
Crossbreeding for Higher Yield and Resilience · Nov 2019
Yin, X., and D. Hedgecock. 2019. Bayesian hierarchical modeling of yield in incomplete diallel crosses of the Pacific oyster Crassostrea gigas. Aquaculture 5…
Heterosis for Yield and Crossbreeding of the Pacific Oyster Crassostrea Gigas
Crossbreeding for Higher Yield and Resilience · Nov 2019
Hedgecock, D., and J. P. Davis. 2007. Heterosis for yield and crossbreeding of the Pacific oyster Crassostrea gigas. Aquaculture 272S1: S17–S29. This paper p…
Genomic Approaches and Tool Development
Characterization of 79 microsatellite DNA markers in the Pacific oyster Crassostrea gigas
Genomic Approaches and Tool Development · Nov 2019
Li, G., S. Hubert, K. Bucklin, V. Ribes, and D. Hedgecock. 2003. Characterization of 79 microsatellite DNA markers in the Pacific oyster Crassostrea gigas. M…
Widespread null alleles and poor cross-species amplification of microsatellite DNA loci cloned from the Pacific oyster (Crassostrea gigas)
Genomic Approaches and Tool Development · Nov 2019
Hedgecock, D., G. Li, S. Hubert, K. Bucklin, and V. Ribes. 2004. Widespread null alleles and poor cross-species amplification of microsatellite DNA loci clon…
Linkage Maps of Microsatellite DNA Markers for the Pacific Oyster Crassostrea Gigas
Genomic Approaches and Tool Development · Nov 2019
Hubert, S., and D. Hedgecock. 2004. Linkage maps of microsatellite DNA markers for the Pacific oyster Crassostrea gigas. Genetics 168:351-362.
The Case for Sequencing the Pacific Oyster Genome
Genomic Approaches and Tool Development · Nov 2019
Hedgecock, D., P. M. Gaffney, P. Goulletquer, X. Guo, K. Reece, and G. W. Warr. 2005. The case for sequencing the Pacific oyster genome. Journal of Shellfish…
Transcriptomic Analysis of Growth Heterosis in Larval Pacific Oysters (Crassostrea Gigas)
Genomic Approaches and Tool Development · Nov 2019
Hedgecock, D., J.-Z. Lin, S. DeCola, C. Haudenschild, E. Meyer, D. T. Manahan, and B. Bowen. 2007. Transcriptomic analysis of growth heterosis in larval Paci…
Expression of the Pacific oyster mitochondrial genome: Variation among loci and evidence for regulation by nuclear-cytoplasmic interaction
Genomic Approaches and Tool Development · Nov 2019
Curole, J. P., E. Meyer, D. T. Manahan and D. Hedgecock. 2009. Expression of the Pacific oyster mitochondrial genome: Variation among loci and evidence for r…
Centromere-mapping in triploid families of the Pacific oyster Crassostrea gigas (Thunberg)
Genomic Approaches and Tool Development · Nov 2019
Hubert, S., E. Cognard, and D. Hedgecock. 2009. Centromere-mapping in triploid families of the Pacific oyster Crassostrea gigas (Thunberg). Aquaculture 288:1…
De novo assembly of the Manila clam Ruditapes philippinarum transcriptome provides new insights into expression bias, mitochondrial doubly uniparental inheritance and sex determination
Genomic Approaches and Tool Development · Nov 2019
Ghiselli, F., L. Milani, P. L. Chang, D. Hedgecock, J. P. Davis, S. V. Nuzhdin, and M. Passamonti. 2012. De novo assembly of the Manila clam Ruditapes philip…
The Oyster Genome Reveals Stress Adaptation and Complexity of Shell Formation.
Genomic Approaches and Tool Development · Nov 2019
Zhang, G., X. Fang, X. Guo, L. Li, R. Luo, F. Xu, P. Yang, L. Zhang, X. Wang, H. Qi, Z. Xiong, H. Que, Y. Xie, P. W. H. Holland, J. Paps, Y. Zhu, F. Wu, Y. C…
Second-generation linkage maps for the Pacific oyster Crassostrea gigas reveal errors in assembly of genome scaffolds
Genomic Approaches and Tool Development · Nov 2019
Hedgecock, D., G. Shin, A.Y. Gracey, D. Van Den Berg and M.P. Samanta. 2015. Second-generation linkage maps for the Pacific oyster Crassostrea gigas reveal e…
Inheritance of high-resolution melting profiles in assays targeting single nucleotide polymorphisms in protein-coding sequences of the Pacific oyster Crassostrea gigas:
Genomic Approaches and Tool Development · Nov 2019
Sun, X.J., G. Shin, and D. Hedgecock. 2015. Inheritance of high-resolution melting profiles in assays targeting single nucleotide polymorphisms in protein-co…
Kumamoto Oysters
The status of the Kumamoto oyster Crassostrea sikamea (Amemiya 1928) in U.S. commercial brood stocks
Kumamoto Oysters · Nov 2019
Hedgecock, D., M.A. Banks and D.J. McGoldrick. 1993. The status of the Kumamoto oyster Crassostrea sikamea (Amemiya 1928) in U.S. commercial brood stocks. Jo…
Gametic incompatibility and genetic divergence of Pacific and Kumamoto oysters, Crassostrea gigas and Crassostrea sikamea
Kumamoto Oysters · Nov 2019
Banks, M.A., D.J. McGoldrick and D. Hedgecock. 1994. Gametic incompatibility and genetic divergence of Pacific and Kumamoto oysters, Crassostrea gigas and Cr…
Occurrence of the Kumamoto oyster Crassostrea sikamea in the Ariake Sea, Japan
Kumamoto Oysters · Nov 2019
Hedgecock, D., G. Li, M. A. Banks, and Z. Kain. 1999. Occurrence of the Kumamoto oyster Crassostrea sikamea in the Ariake Sea, Japan. Marine Biology (Berlin)…
The Kumamoto oyster Crassostrea sikamea is neither rare nor threatened by hybridization in the northern Ariake Sea, Japan
Kumamoto Oysters · Nov 2019
Camara, M. D., J. P. Davis, M. Sekino, D. Hedgecock, G. Li, C. J. Langdon, and S. Evans. 2008. The Kumamoto oyster Crassostrea sikamea is neither rare nor th…
Mutation and Inbreeding Depression
Fixation, segregation and linkage of allozyme loci in inbred families of the Pacific oyster Crassostrea gigas (Thunberg):
Mutation and Inbreeding Depression · Nov 2019
McGoldrick, D. J., and D. Hedgecock. 1997. Fixation, segregation and linkage of allozyme loci in inbred families of the Pacific oyster Crassostrea gigas (Thu…
High Genetic Load in the Pacific Oyster Crassostrea Gigas
Mutation and Inbreeding Depression · Nov 2019
Launey, S. and D. Hedgecock. 2001. High genetic load in the Pacific oyster Crassostrea gigas. Genetics 159:255-265.
Quantitative Trait Locus Analysis of stage-specific inbreeding depression in the Pacific oyster Crassostrea gigas
Mutation and Inbreeding Depression · Nov 2019
Plough, L. V., and D. Hedgecock. 2011. Genome-wide analysis of stage-specific inbreeding depression in the Pacific oyster Crassostrea gigas. Genetics 189:1-1…
Genetic inviability is a major driver of type III survivorship in experimental families of a highly fecund marine bivalve
Mutation and Inbreeding Depression · Nov 2019
Plough, L.V., G. Shin and D. Hedgecock. 2016. Genetic inviability is a major driver of type III survivorship in experimental families of a highly fecund mari…
POMS Resistance
Mass Selection for Survival and Resistance to OsHV-1 Infection in Crassostrea Gigas Spat in Field Conditions: Response to Selection after Four Generations.
POMS Resistance · Nov 2019
Dégremont, L., Nourry, M. & Maurouard, E. 2015. Mass selection for survival and resistance to OsHV-1 infection in Crassostrea gigas spat in field conditions:…
Genetic Improvement for Disease Resistance in Oysters: A Review
POMS Resistance · Nov 2019
Dégremont, L., Garcia, C. & Allen, S.K., Jr. 2015. Genetic improvement for disease resistance in oysters: A review. Journal of Invertebrate Pathology 131, 22…
Genetic Variation in Pacific Oysters (Crassostrea Gigas) for Resistance to Ostreid Herpesvirus-1
POMS Resistance · Nov 2019
Kube, P.D., Dove, M.C., Cunningham, M., Kirkland, P.D., O’Connor, W.A., & Elliott, N.G. (2017) Genetic variation in Pacific oysters (Crassostrea gigas) for r…
A Genome-wide Association Study for Host Resistance to Ostreid Herpesvirus in Pacific Oysters (Crassostrea Gigas)
POMS Resistance · Nov 2019
Gutierrez, A.P., Bean, T.P., Hooper, C., Stenton, C.A., Sanders, M.B., Paley, R.K., Rastas, P., Bryrom, M., Matika, O. & Houston, R.D., 2018. A genome-wide a…
Applications of Next Generation Sequencing in Sessile Marine Invertebrates
POMS Resistance · Nov 2019
Kitapci, T.H. 2018. Applications of next generation sequencing in sessile marine invertebrates. PhD dissertation, University of Southern California.
Genetic Variation in Pacific Oysters (Crassostrea Gigas) for Resistance to Ostreid Herpesvirus-1 Abstract
POMS Resistance · Nov 2019
Kube, P.D., Dove, M.C., & Cunningham, M. (2018) Genetic variation in Pacific oysters (Crassostrea gigas) for resistance to ostreid herpesvirus-1. Abstract of…
Mapping Genes Conferring Resistance to OsHV-1 in the Pacific Oyster
POMS Resistance · Nov 2019
Kitapci, T.H., Burge, C.A., Closek, C., Friedman, C. & Hedgecock, D. 2018. Mapping genes conferring resistance to OsHV-1 in the Pacific oyster. Abstract of p…
A Literature Review as an Aid to Identify Strategies for Mitigating Ostreid Herpesvirus
POMS Resistance · Nov 2019
Rodgers, C., Arzul, I., Carrasco, N. and Furones Nozal, D., 2018. A literature review as an aid to identify strategies for mitigating ostreid herpesvirus 1 i…
Physiological Basis of Hybrid Vigor and Resilience
Feeding behavior and metabolic efficiency contribute to growth heterosis in Pacific oysters
Physiological Basis of Hybrid Vigor and Resilience · Nov 2019
Bayne, B. L., D. Hedgecock, D. McGoldrick, and R. Rees. 1999. Feeding behavior and metabolic efficiency contribute to growth heterosis in Pacific oysters [Cr…
Physiological bases of genetically determined variation in growth of marine invertebrate larvae: A study of growth heterosis in the bivalve Crassostrea gigas
Physiological Basis of Hybrid Vigor and Resilience · Nov 2019
Pace, D. A., A. G. Marsh, P. Leong, A. Green, D. Hedgecock, and D. T. Manahan. 2006. Physiological bases of genetically determined variation in growth of mar…
Separating the nature and nurture of energy allocation in response to global change
Physiological Basis of Hybrid Vigor and Resilience · Nov 2019
Applebaum, S.L., T.-C.F. Pan, D. Hedgecock and D.T. Manahan. 2014. Separating the nature and nurture of energy allocation in response to global change. Integ…
Metabolic Costs of Calcification in Bivalve Larvae under Experimental Ocean Acidification
Physiological Basis of Hybrid Vigor and Resilience · Nov 2019
Frieder, C.A., S.L. Applebaum, T.-C. Francis Pan, D. Hedgecock and D. T. Manahan. 2017. Metabolic costs of calcification in bivalve larvae under experimental…
Polyploids in Shellfish Aquaculture
Viable Tetraploids in the Pacific Oyster (Crassostrea Gigas Thunberg) Produced by Inhibiting Polar Body in Eggs from Triploids
Polyploids in Shellfish Aquaculture · Nov 2019
Guo, X.M., and S. K. Allen. 1994. Viable tetraploids in the Pacific oyster (Crassostrea gigas Thunberg) produced by inhibiting polar body in eggs from triplo…
Farming Triploid Oysters
Polyploids in Shellfish Aquaculture · Nov 2019
Nell, J. A. 2002. Farming triploid oysters. Aquaculture 210:69–88.
Estimation of Preferential Pairing Rates in Second-Generation Autotetraploid Pacific Oysters (Crassostrea Gigas)
Polyploids in Shellfish Aquaculture · Nov 2019
Curole, J. P., and D. Hedgecock. 2005. Estimation of preferential pairing rates in second-generation autotetraploid Pacific oysters (Crassostrea gigas). Gene…
Polyploid Fish and Shellfish: Production, Biology and Applications to Aquaculture for Performance Improvement and Genetic Containment
Polyploids in Shellfish Aquaculture · Nov 2019
Piferrer, F., A. Beaumont, J-C Falguière, M. Flajšhans, P. Haffray, and L. Colombo. 2009. Polyploid fish and shellfish: Production, biology and applications…
All-triploid Pacific Oysters (Crassostrea Gigas Thunberg) Produced by Mating Tetraploids and Diploids
Polyploids in Shellfish Aquaculture · Nov 2019
Guo, X.M., G. A. DeBrosse, and S. K. Allen. 1996. All-triploid Pacific oysters (Crassostrea gigas Thunberg) produced by mating tetraploids and diploids. Aqua…
Optimal Chemical Triploid Induction in Geoduck Clams, Panopea Abrupta, by 6-Dimethylaminopurine
Polyploids in Shellfish Aquaculture · Nov 2019
Vadopalas, B., and J. P. Davis. 2004. Optimal chemical triploid induction in geoduck clams, Panopea abrupta, by 6-dimethylaminopurine. Aquaculture 230: 29-40.
Field Observations on Growth, Gametogenesis and Sex Ratio of Triploid and Diploid Mytilus Edulis
Polyploids in Shellfish Aquaculture · Nov 2019
Brake, J. W., J. Davidson, and J. Davis. 2004. Field observations on growth, gametogenesis and sex ratio of triploid and diploid Mytilus edulis. Aquaculture…
Maturation, Spawning, and Fecundity of the Farmed Pacific Geoduck Panopea Generosa in Puget Sound, Washington
Polyploids in Shellfish Aquaculture · Nov 2019
Vadopalas, B., J. P. Davis, and C. S. Friedman. 2015. Maturation, spawning, and fecundity of the farmed Pacific geoduck Panopea generosa in Puget Sound, Wash…
Sex Determination
Genetic determinants of protandric sex in the Pacific oyster, Crassostrea gigas Thunberg
Sex Determination · Nov 2019
Guo, X., D. Hedgecock, W. K. Hershberger, K. Cooper, and S. K. Allen, Jr. 1998. Genetic determinants of protandric sex in the Pacific oyster, Crassostrea gig…
Sex Determination: Genetic Models for Oysters.
Sex Determination · Nov 2019
Hedrick, P. W., and D. Hedgecock. 2010. Sex determination: Genetic models for oysters. Journal of Heredity 101: 602-611.
Sustainable Aquaculture
Nonnative Oysters in the Chesapeake Bay
Sustainable Aquaculture · Jul 2019
Committee on Nonnative Oysters in the Chesapeake Bay [J. Anderson and D. Hedgecock (Co-Chairs), M. Berrigan, K. Criddle, W. Dewey, S. Ford, P. Goulletquer, R…
Genetics of Shellfish on a Human-Dominated Planet
Sustainable Aquaculture · Jul 2019
Hedgecock, D. 2011. Genetics of Shellfish on a Human-Dominated Planet. Chapter 12, in: Shellfish Aquaculture and the Environment. Shumway, S. E. (editor). Wi…
Shellfish Aquaculture and the Environment: An Industry Perspective.
Sustainable Aquaculture · Jul 2019
Dewey, W., J. P. Davis, and D. C. Cheney. 2012. Shellfish aquaculture and the environment: an industry perspective. Chapter 2, in: Shellfish Aquaculture and…
Aquaculture: the Next Wave of Domestication.
Sustainable Aquaculture · Jul 2019
Hedgecock, D. 2012. Aquaculture: the Next Wave of Domestication. In: Biodiversity in Agriculture: Domestication, Evolution, and Sustainability. Gepts, P. L.,…
Boom-and-Bust Production Cycles in Animal Seafood Aquaculture.
Sustainable Aquaculture · Jul 2019
You, W., and D. Hedgecock. 2018. Boom-and-bust production cycles in animal seafood aquaculture. Reviews in Aquaculture, available online. https://onlinelibra…